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|`--pathogen`| Apply CMAPLE tree search algorithm if sequence divergence is low, otherwise, apply IQ-TREE algorithm. |
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|`--pathogen-force`| Apply CMAPLE tree search algorithm regardless of sequence divergence. |
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|`-alrt`| Specify number of replicates (>=1000) to perform SH-like approximate likelihood ratio test (SH-aLRT) ([Guindon et al., 2010]). |
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|`-T`| Specify the number of CPU cores to use only for the SH-aLRT test. If `-T AUTO` is specified, IQ-TREE will use all available cores. NOTE: this option has no effect on tree search, which is still single-threaded. |
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|`--alrt <num_rep>`| Specify the number of replicates to compute SH-like approximate likelihood ratio test (SH-aLRT) ([Guindon et al., 2010]). |
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|`--sprta`| Compute SPRTA ([De Maio et al., 2024]) branch supports. |
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|`--zero-branch-supp`| Compute SPRTA supports for zero-length branches.|
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|`--out-alter-spr`| Output alternative SPRs and their SPRTA supports.|
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|`-T <num_thread>`| Specify the number of threads used for computing branch supports (SH-aLRT or SPRTA). If `-T AUTO` is specified, all available cores will be used.|
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### Example usages:
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@@ -469,9 +472,15 @@ and remove `--pathogen` option to invoke the default IQ-TREE machinery.
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* Infer a tree like above and additionally assign branch supports using SH-aLRT test
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