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update doc and recipes
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doc/AliSim.md

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doc/Command-Reference.md

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layout: userdoc
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title: "Command Reference"
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author: 95438353+HectorBanos, Diep Thi Hoang, Dominik Schrempf, Heiko Schmidt, Jana Trifinopoulos, Minh Bui, Thomaskf, Trongnhan Uit
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date: 2024-06-28
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date: 2025-03-28
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docid: 19
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doctype: manual
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|----------|------------------------------------------------------------------------------|
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| `--pathogen` | Apply CMAPLE tree search algorithm if sequence divergence is low, otherwise, apply IQ-TREE algorithm. |
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| `--pathogen-force` | Apply CMAPLE tree search algorithm regardless of sequence divergence. |
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| `-alrt` | Specify number of replicates (>=1000) to perform SH-like approximate likelihood ratio test (SH-aLRT) ([Guindon et al., 2010]). |
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| `-T` | Specify the number of CPU cores to use only for the SH-aLRT test. If `-T AUTO` is specified, IQ-TREE will use all available cores. NOTE: this option has no effect on tree search, which is still single-threaded. |
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| `--alrt <num_rep>` | Specify the number of replicates to compute SH-like approximate likelihood ratio test (SH-aLRT) ([Guindon et al., 2010]). |
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| `--sprta` | Compute SPRTA ([De Maio et al., 2024]) branch supports. |
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| `--sprta-zero-branch`| Compute SPRTA supports for zero-length branches.|
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| `--sprta-other-places` | Output alternative SPRs and their SPRTA supports.|
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| `-T <num_thread>` | Specify the number of threads used for computing branch supports (SH-aLRT or SPRTA). If `-T AUTO` is specified, all available cores will be used.|
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### Example usages:
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* Infer a tree like above and additionally assign branch supports using SH-aLRT test
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with 1000 replicates using 4 CPU cores:
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iqtree2 -s data.phy --pathogen --alrt 1000 -T 4 --prefix pathogen
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iqtree2 -s data.phy --pathogen --alrt 1000 -T 4 --prefix pathogen_sh_alrt
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The tree `pathogen.treefile` will contain branch supports for all internal branches.
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The output file `pathogen_sh_alrt.treefile` will contain SH-aLRT branch supports for all internal branches.
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* Infer a tree like above and additionally assign SPRTA branch supports:
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iqtree2 -s data.phy --pathogen-force --sprta --prefix pathogen_sprta
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The output file `pathogen_sprta.nex` will contain SPRTA branch supports for all (internal and external) branches.
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Ultrafast bootstrap parameters
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------------------------------
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[Anisimova and Gascuel 2006]: https://doi.org/10.1080/10635150600755453
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[Anisimova et al., 2011]: https://doi.org/10.1093/sysbio/syr041
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[De Maio et al., 2023]: https://doi.org/10.1038/s41588-023-01368-0
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[De Maio et al., 2024]: https://doi.org/10.1101/2024.10.21.619398
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[Felsenstein, 1985]: https://doi.org/10.2307/2408678
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[Flouri et al., 2015]: https://doi.org/10.1093/sysbio/syu084
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[Gadagkar et al., 2005]: https://doi.org/10.1002/jez.b.21026

doc/Complex-Models.md

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layout: userdoc
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title: "Complex Models"
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author: 928003585, 95438353+HectorBanos, Dominik Schrempf, Jana Trifinopoulos, Minh Bui, Rob Lanfear, Thomaskf, Trongnhan Uit
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date: 2025-01-08
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date: 2025-03-12
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If you use MixtureFinder in a publication please cite:
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> __H. Ren, T.K.F. Wong, B.Q. Minh, R. Lanfear__ (2024) MixtureFinder: Estimating DNA mixture models for phylogenetic analyses. _Mol. Biol. Evol_. <https://doi.org/10.1093/molbev/msae264>
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> __H. Ren, T.K.F. Wong, B.Q. Minh, R. Lanfear__ (2025) MixtureFinder: Estimating DNA mixture models for phylogenetic analyses. _Mol. Biol. Evol_. <https://doi.org/10.1093/molbev/msae264>
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