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DESCRIPTION
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Package: immunarch
Type: Package
Title: Multi-Modal Immune Repertoire Analytics for Immunotherapy and Vaccine Design in R
Version: 0.10.3.9002
Authors@R: c(
person("Vadim I.", "Nazarov", , "support@immunomind.com", role = c("aut", "cre"),
comment = c(ORCID = "0000-0003-3659-2709")),
person("Vasily O.", "Tsvetkov", , role = "aut"),
person("Aleksandr A.", "Popov", , role = "aut"),
person("Ivan", "Balashov", , role = "aut")
)
Contact: support@immunomind.com
Description: A comprehensive analytics framework for building reproducible pipelines on T-cell and B-cell immune receptor repertoire data.
Delivers multi-modal immune profiling (bulk, single-cell, CITE-seq/AbSeq, spatial, immunogenicity data),
feature engineering (ML-ready feature tables and matrices), and biomarker discovery workflows
(cohort comparisons, longitudinal tracking, repertoire similarity, enrichment).
Provides a user-friendly interface to widely used AIRR methods —
clonality/diversity, V(D)J usage, similarity, annotation, tracking, and many more.
Think Scanpy or Seurat, but for AIRR data, a.k.a. Adaptive Immune Receptor Repertoire, VDJ-seq, RepSeq, or
VDJ sequencing data. A successor to our previously published "tcR" R package (Nazarov 2015).
License: Apache License (>= 2.0)
URL: https://immunomind.github.io/docs/, https://github.com/immunomind/immunarch/, https://immunarch.com/
BugReports: https://github.com/immunomind/immunarch/issues
Depends:
R (>= 4.2.0),
ggplot2 (>= 3.1.0),
immundata (>= 0.0.5),
patchwork
Imports:
dplyr,
dtplyr (>= 1.0.0),
data.table (>= 1.12.6),
cli,
pheatmap (>= 1.0.12),
reshape2 (>= 1.4.2),
circlize,
airr,
Rcpp (>= 1.0),
magrittr,
methods,
scales,
rlang,
plyr,
stringdist,
readr,
stringr,
tibble,
tidyselect,
tidyr,
ape,
doParallel,
rlist,
utils,
glue,
checkmate,
duckplyr (>= 1.1.2),
dbplyr,
lifecycle,
purrr,
stats,
vctrs,
ggthemes,
ggsci
LinkingTo: Rcpp
Suggests:
knitr (>= 1.8),
roxygen2 (>= 3.0.0),
testthat (>= 3.0.0),
pkgdown (>= 0.1.0),
assertthat,
rmarkdown,
factoextra (>= 1.0.4),
fpc,
ggpubr (>= 0.2),
ggraph,
ggseqlogo,
igraph,
phangorn,
ggalluvial (>= 0.10.0),
UpSetR (>= 1.4.0),
ggrepel (>= 0.8.0),
shiny (>= 1.4.0),
shinythemes,
quarto,
MASS (>= 7.3),
Rtsne (>= 0.15)
VignetteBuilder:
knitr,
quarto
Encoding: UTF-8
RoxygenNote: 7.3.3
LazyData: true
LazyDataCompression: xz
Roxygen: list(markdown = TRUE)
Config/Needs/website: rmarkdown
Config/testthat/edition: 3